Johnson & Johnson is planning to ask U.S. federal regulators early this week to authorize a booster shot of its coronavirus vaccine, according to officials familiar with the company’s plans. The firm is the last of the three federally authorized vaccine providers to call for extra injections, amid mounting evidence that at least older adults and others in high-risk groups need more protection.
Federal officials have become increasingly worried that the more than 15 million Americans who received the Johnson & Johnson vaccine face too much risk of severe Covid-19. The Food and Drug Administration on Friday scheduled an Oct. 15 meeting of its expert advisory committee to discuss whether to grant emergency use authorization of a booster shot of the vaccine.
That is part of a broader effort by the government to shore up the protection provided by all three vaccines. Regulators last month authorized a booster shot for many recipients of Pfizer-BioNTech’s vaccine and are contemplating doing the same this month for recipients of Moderna’s.
The fact that the advisory committee meeting on Johnson & Johnson was scheduled even before the company filed an application to the Food and Drug Administration reflects a particular sense of urgency in the Biden administration to provide more protection to recipients of that vaccine.
Although the federal government has emphasized for months that all three vaccines are highly effective, a recent study by the Centers for Disease Control and Prevention found that Johnson & Johnson’s single-dose vaccine was only 71 percent effective against hospitalization from Covid, compared with 88 percent for Pfizer-BioNTech’s vaccine and 93 percent for Moderna’s.
“Real-world data suggest that the two-dose Moderna and Pfizer-BioNTech mRNA vaccine regimens provide more protection” than the single dose of Johnson & Johnson, the researchers said. Other research found that Johnson & Johnson recipients were more likely to have breakthrough infections or symptomatic Covid than recipients of the other two vaccines.
Johnson & Johnson cites some studies with better results: A study of nearly two million people, funded by the company, estimated that the vaccine was 81 percent effective against hospitalization. Other research suggests that protection from Johnson & Johnson’s vaccine does not wane over time like protection from Pfizer-BioNTech’s vaccine.
Nonetheless, Johnson & Johnson now appears to agree with federal officials that a single shot of its vaccine is not enough.
Last month, the company announced that a second dose, given two months after the first, increased the vaccine’s effectiveness against symptomatic Covid by about 22 percentage points, to 94 percent. Johnson & Johnson also said two shots were 100 percent effective against severe disease, although that estimate was less conclusive.
Andrew Wiggins, the Golden State Warriors guard who had resisted getting a Covid-19 vaccine, has received one, the team’s coach, Steve Kerr, told reporters on Sunday.
This means Wiggins will be able to play in home games in San Francisco, since city ordinances require individuals to be fully vaccinated to enter facilities such as indoor gyms. Wiggins had attempted to circumvent those restrictions by filing for a religious exemption, which the N.B.A. denied.
The N.B.A. had said publicly that if players in markets with similar mandates — meaning the Nets and the Knicks, who play in New York, and the Warriors, who play in San Francisco — could not play because of their unvaccinated status, they could lose salary.
Initially, it seemed Wiggins would hold out and miss the home games. He told reporters last week that his back “was against the wall, but I’m just going to keep fighting for what I believe.”
The league has said in recent days that 95 percent of N.B.A. players had received at least one dose of a Covid-19 vaccine. The players’ union has rejected instituting a leaguewide vaccine mandate. Wiggins was one in a small group of prominent players who were unvaccinated. But Wiggins did receive support from vaccinated teammates like Draymond Green, who said he wouldn’t push Wiggins to take the vaccine.
“To me, it feels like it has turned into a political war,” Green told reporters last week. “When you are talking about vaccination and nonvaccinated, I think it’s become very political. And for someone who is not extremely into politics, when you make something so political and not everyone is into politics, then you can also turn those people off. I think there is something to be said for people’s concern about something that’s being pressed so hard. Like, why are you pressing this so hard?”
Green’s comments received support from the N.B.A.’s biggest star, LeBron James, as well as a frequent critic of the N.B.A., Senator Ted Cruz, Republican from Texas. The senator also said in a Twitter post on Wednesday, “I stand with Andrew Wiggins,” as well as other unvaccinated players, including Jonathan Isaac of the Orlando Magic and the Washington Wizards’ Bradley Beal.
Source: NYT > Top Stories